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           ID D N U  |  iddnu@suntrap.com   |   www.suntrap.com



                              nism of patients infected with SARS-CoV-2, the Sun-  the virus load in the mouth and nose, and reduce the
                              trap’s  research  team  optimized  and  developed  dif-  probability of aggravation; (2) it inhibits the combi-
                              ferent  clinical  protocols.  The  basic  formulation  was   nation of SARS-CoV-2 and sialic acid, and then helps
                              completed in November 2020.                  the human immune system to recognize the viruses;
                                                                           (3) LeSoleil-T is positively charged and can effectively
                              LeSoleil  the  broad-spectrum  anti-COVID-19 protec-
                                                                           adsorb negatively charged SARS-CoV-2 virus, so as to
                              tive  and  therapeutic  spray  include  three  types:  Le-
                                                                           inhibit the transfer of viruses in host cells; (4) it can
                              Soleil-01,  oral  spray;  LeSoleil-02,  nasal  spray;  and
                                                                           inhibit the production of pro-inflammatory factors to
                              LeSoleil-02 , preventive and therapeutic ultrasonic at-
                                      +
                                                                           inhibit inflammation, and effectively treat upper re-
                              omizing  inhaler.  The  broad-spectrum  anti-COVID-19
                                                                           spiratory tract inflammation and other related symp-
                              protective  and  therapeutic  spray  is  suitable  for
                                                                           toms caused by COVID-19; (5) it has a dynamic con-
                              COVID-19  protection  and  patients  with  asymptom-
                                                                           sistency similar to that of the mucus of the oral cavity
                              atic  or  mild  infection.  LeSoleil-03  is  a  therapeutic
                                                                           and  nasal  cavity,  which  can  make  the  broad-spec-
                              “anti-COVID-19  aerosol  inhaler”,  which  is  suitable
                                                                           trum  anti-coronavirus  protective  and  therapeutic
                              for  patients  with  moderate  and  severe  SARS-CoV-2
                                                                           spray evenly adhere to the mucous membrane after
                              infection. In addition, LeSoleil-03 can also be used in
                                                                           reaching the oral cavity and nasal cavity, forming a
                              patients with pulmonary fibrosis sequelae caused by
                                                                           “biological protective film” that lasts for a long time.
                              SARS-CoV-2 infection. All of these three preparations
                                                                           For some asymptomatic or mildly infected people, a
                              are suitable for children, adults and the elderly.
                                                                           small amount of the virus will be excreted when they
                              The  LeSoleil  broad-spectrum  anti-coronavirus pro-  cough,  sneeze  or  exhale.  After  using  a  broad-spec-
                              tective  and  therapeutic  spray  is  portable  and  easy   trum  anti-coronavirus  protective  and  therapeutic
                              to  use.  It  effectively  prevents  healthy  people  from   spray, the active ingredient LeSoleil-T can inhibit the
                              infection and blocks the spread of SARS-CoV-2 from   excreted virus and block the route of virus transmis-
                              asymptomatic  and  mild  COVID-19  patients.  LeSoleil   sion to achieve a more extensive protective effect.
                              broad-spectrum  anti-coronavirus  protective  and
                                                                           For patients with moderate and severe SARS-CoV-2
                              therapeutic spray can cope with the prevention and
                                                                           infections, it is recommended to use LeSoleil-03 twice
                              treatment  of  SARS-CoV-2  and  variant  strains  (e.g.,
                                                                           a day to treat the infection and inflammation in the
                              Delta and Omicron.). In addition, the preclinical study
                                                                           respiratory  tract  and  lungs.  It  is  convenient  for  pa-
                              conducted by the Suntrap team revealed that LeSoleil
                                                                           tients to use, including dissolving LeSoleil-03 in ster-
                              can also be used for upper respiratory tract infections
                                                                           ile water and then inhaling through the respiratory
                              caused by influenza viruses and mutant strains (e.g.,
                                                                           tract directly to the lungs via a ventilator and medical
                              H1N1, H5N1, H7N1, H7N2, H7N3, H7N7, H7N9, H9N2
                                                                           atomizing  device.  The  characteristics  and  efficacies
                              and H10N8). The new corresponding symptoms still
                                                                           of LeSoleil-03 are as follows: (1) it has a small parti-
                              need to be verified by clinical research.
                                                                           cle size and no foreign body sensation, and it is easy
                              The  characteristics  of  LeSoleil  broad-spectrum  an-  to  inhale  with  medical  machinery  or  a  small  medi-
                              ti-coronavirus protective and  therapeutic spray are   cal-grade  ultrasonic  atomization  device  and  reach
                              as follows: (1) it can inhibit virus replication, control   the lungs through the bronchus to avoid the first-pass
                                                                           effect; (2) the local drug concentration is high, and it
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